Johnny Depp and Queen Elizabeth are 20th cousins ..!

Johnny Depp might be upset about being left off the royal wedding guest list now that it's been revealed that he and Queen Elizabeth are reportedly distant cousins.

According to the Daily Mail, the "Pirates of the Caribbean: On Stranger Tides" star and the British monarch both share the same bloodline. One branch of Depp's ancestors are descended from 15th-century aristocrats Sir William Gascoigne and his wife Margaret Percy, who hailed from Yorkshire, England.

Margaret was the daughter of the third Earl of Northumberland and also a direct descendent of King Edward III. Queen Elizabeth is Edward III's great-granddaughter, 17 times removed, and Depp's cousin, 20 times removed.

Meanwhile, it's also been said that Lady Gaga is related to another music icon. New England Historic Genealogical Society specialist Chris Child tells the Boston Globe that Madonna and Gaga are ninth cousins, once removed.

"When I saw that Lady Gaga had French Canadian ancestry, I thought there might be something there," he said of the New Yorker, who has been criticized in the past for copying Madonna's music and style. According to Child, both women are descended from a French farming couple who moved to Quebec in the 1600s.

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